Lipases, Immobilized
Sustine® 110 IM
Sustine® 110 IM is a non-specific immobilized lipase that offers cost-efficient recyclability and works well with stereoselective hydrolysis of esters, transesterification and esterification of acids, and acylation of amines.
The biocatalytic properties of Sustine® 110 IM are already being used in the manufacturing of known commercial active pharmaceutical ingredients (APIs), such as:
- Molnupiravir
- Trandolapril
- Amino hydroxypiperidine derivatives
- Pimecrolimus
It is also used as a catalyst to manufacture key agro intermediates (AIs):
- S-metolachlor and S-dimethenamid – Herbicide intermediate (S)-MOIPA
Other commercial APIs/AIs that use Sustine® 110 IM include:
- Moxifloxacin
- Posaconazole
- S-Flurbiprofen
- Ketorolac
- Chloramphenicol
- Analogues of mevinic acid
- (S)-1-(2-furyl)ethanol
- Intermediates in the synthesis of Stagonolide E, Pyrenophorol and Decarestrictin L
- Naphthofurandion derivative
Sustine® 110 IM is identical to the former Novozymes product, Novozym® 435.
Product features, details and benefits
Stereoselective hydrolysis of esters, transesterification, and esterification of acids, and acylation of amines.
Broad specificity
Immobilized granulate (Yes)
Very broad temperature stability (up to 100℃)
Organic solvent friendly
Widely used across many commercial applications
APIs:
- Molnupiravir
- Trandolapril
- Amino hydroxypiperidine derivatives
- Pimecrolimus
Agro intermediates
- S-metolachlor and S-dimethenamid – Herbicide intermediate (S)-MOIPA
FAQ
Testing one of our products in your own production is the best way to experience all the benefits.
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