Sustine® 120 IM

Sustine® 120 IM

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Sustine^® 120 IM is a 1,3 immobilized lipase that offers recyclability and works well with stereoselective hydrolysis and desymmetrization of esters.
Sustine^® 120 IM can be applied in the manufacturing of commercial active pharmaceutical ingredients (APIs), such as:

Pregabalin

As well as intermediates/transformations for:

Metronidazole, nimorazole and benznidazole (by Michael addition)
Sugar-containing coumarins, such as warfarin, armillarisin and novobiocin
Nucleoside analogues of uridine, such as azidothymidine, doxifluridine and telbivudine

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Product features, details and benefits

Benefits

Recyclable
Stereoselective hydrolysis of esters, transesterification, and esterification of acids, and acylation of amines.

1,3 specific lipase
Immobilized granulate (Yes)

Organic solvent friendly

Broad temperature stability

Details

Safe handling

FAQ

Can this product be used in both aqueous and organic solvent processes?

Being immobilized, does this product work well at a moderate temperature range?

How about suitability in stirred-batch tanks versus continuous fixed-bed reactors?

Testing one of our products in your own production is the best way to experience all the benefits.

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