Yeast propagation: achieve consistent results at every propagation

Improve your yeast management with consistently high cell count propagations. Skip the lab steps, cut variation and get reliable fermentation results with frozen liquid yeast SmartBev™ FLY.

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The evolving role of yeast propagation

Since 1883, yeast propagation has been at the heart of great brewing. Today, brewers need more than a growing yeast culture. They need the right yeast cell count, high viability and strong vitality to ensure reliable fermentation and consistent beer quality from batch to batch.

As breweries expand and multi-site production becomes more complex, they need solutions that reduce variation, contamination risk and laboratory effort while providing the speed and flexibility to adapt to changing production demands. 

Common challenges in yeast propagation

Traditional yeast propagation from slants can create planning, quality and operational challenges. Here are some of the most common hurdles breweries face.

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    Inconsistent batch-to-batch propagation

    Propagation conditions such as temperature, aeration and mixing can vary from slant to Carlsberg flask. This can lead to inconsistent yeast cell count, viability and vitality, affecting inoculation, generation-zero fermentation and beer quality.

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    Variable yeast culture quality

    Traditional propagation must be planned days in advance. Schedule changes or failed propagations can cause delays, while sites without dedicated labs may depend on externally produced yeast starters, increasing costs and limiting production flexibility.

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    High labor and resource demands

    Traditional propagation requires skilled personnel, time and laboratory resources. Preparing wort, handling Carlsberg flasks and managing inoculation also involve heavy lifting, hot liquids and pressurized equipment, increasing health, safety and environmental risks.

Reliable yeast propagation with greater production flexibility

SmartBev™ FLY gives breweries a consistent, ready-to-pitch starting point for yeast propagation. By skipping early lab steps and reducing handling, it simplifies workflows, supports faster responses to production changes and helps deliver dependable fermentation performance.

Achieve fast, consistent propagation results

SmartBev™ FLY simplifies yeast propagation by eliminating the earliest cultivation and laboratory propagation steps that can introduce variability. By combining high-purity yeast with a standardized inoculation rate, it delivers consistent yeast viability and reproducible yeast cell counts at the start of every propagation. This provides a reliable foundation for generation-zero fermentation while supporting the highest hygiene and quality standards.

The streamlined process can save up to 10 days in propagation time while reducing operational effort and improving health and safety.

Inspecting beer during production to monitor brewing process consistency.

Increase production flexibility and agility

Keep a reliable yeast supply on-site and ready when production needs change. Stored frozen and ready for yeast pitching in as little as 1.5 hours, SmartBev™ FLY helps breweries respond quickly to schedule changes, seasonal demand and shifting production priorities.

By removing the need for extensive yeast starter preparation and early cultivation steps, breweries gain greater flexibility in production planning while maintaining reliable fermentation performance.

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Secure reliable yeast supply

The SmartBev™ FLY frozen liquid yeast format is supported by a well-established cold supply chain designed to preserve product quality from production to brewery. With a two-year shelf life and no change in performance during storage, breweries can maintain strategic inventory on-site and reduce dependence on complex propagation schedules.

This allows brewers to secure access to high-quality yeast cultures whenever needed, providing greater planning confidence and operational resilience.

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Simplify yeast management without added CAPEX

SmartBev™ FLY helps breweries modernize yeast management without investing in new propagation infrastructure. By reducing the need for dedicated laboratory propagation equipment, specialized handling procedures and associated operational resources, breweries can simplify workflows while reducing complexity.

The result is a more efficient yeast propagation process that supports production goals without major capital investment.

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A new era for yeast: Heritage meets innovation

Novonesis is thrilled to announce the acquisition of two legendary yeast collections from Cara Technology: the Alfred Jørgensen Laboratory and the Scandinavian Brewing Laboratory.

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Get in touch.

Ready to bring consistency to every propagation? Tell us about your production goals, and our brewing experts will help you find the right ready-to-pitch solution.

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Understanding the benefits of frozen liquid yeast

Frozen liquid yeast SmartBev™ FLY provides a standardized inoculation rate at the start of each propagation, reducing the variability associated with preparing a yeast starter through multiple laboratory cultivation steps. This gives breweries a more reproducible starting point for yeast propagation and supports consistent yeast pitching and quality into generation-zero fermentation.

Traditional yeast propagation involves multiple propagation and transfer steps where yeast cultures are handled in open or semi-open environments. Each additional step creates opportunities for contamination. By eliminating the earliest cultivation stages and eliminating open handling requirements, frozen liquid yeast SmartBev™ FLY helps breweries establish a cleaner and more controlled start to brewing yeast propagation.

For brewery groups operating across multiple production sites, maintaining a consistent yeast culture can be challenging. Frozen liquid yeast SmartBev™ FLY enables breweries to start from the same yeast source, quality and condition across locations, helping standardize brewing yeast propagation practices and support more consistent fermentation performance throughout the network.

Every additional propagation stage requires time, equipment, resources and process control. It also increases the potential for variation in yeast viability and yeast vitality. By removing the earliest cultivation stages, SmartBev™ FLY simplifies the path from yeast storage to fermenter, helping breweries reduce process complexity while maintaining propagation quality with the highest purity yeast.

Because SmartBev™ FLY can be stored frozen on-site and prepared for yeast pitching in as little as 1.5 hours, breweries are better positioned to respond to schedule changes, demand fluctuations or unexpected production opportunities without waiting for a new yeast starter to be prepared.

Many breweries maintain multiple yeast strains to produce different beer styles. SmartBev™ FLY allows brewers to keep selected yeast cultures available on-site with a long shelf life, reducing the operational effort required to maintain and propagate multiple strains while preserving flexibility in production planning.

By minimizing laboratory propagation activities, handling steps, hot wort preparation and heavy lifting, frozen liquid yeast SmartBev™ FLY helps reduce several operational risks associated with traditional yeast propagation. This can support safer working conditions, more consistent execution and reduced dependency on specialized propagation expertise and staff.

Simplifying yeast management starts with reducing the number of handling and propagation steps required before pitching. SmartBev™ FLY helps brewers streamline yeast propagation, reduce contamination risks and maintain consistent yeast performance while requiring fewer laboratory resources and less operational effort. By keeping frozen liquid yeast available on-site, breweries can improve production flexibility, simplify yeast stock management and maintain consistent yeast propagation across multiple brewing locations.

Frozen liquid yeast SmartBev™ FLY can be thawed in a 30°C water bath and prepared for pitching in approximately 60-90 minutes. This allows breweries to move from frozen storage to propagation or fermentation quickly, supporting flexible production planning when schedules change.

No. SmartBev™ FLY cells are frozen in an active state and therefore do not require activation before pitching. This helps reduce preparation time and simplifies yeast handling compared with other common yeast propagation approaches.

Yes. SmartBev™ FLY is designed for direct pitching into fermentation or propagation tanks. The product is manufactured under strict quality-control standards to ensure high purity and consistent yeast performance. Since the yeast cells are frozen in an active state, no activation step is required before pitching.

SmartBev™ FLY is supplied with a sterile application set that enables hygienic transfer into breweries' existing systems. The set is designed to support closed handling practices and reduce contamination risks during yeast inoculation. It also supports connection to commonly used valve configurations, helping breweries implement frozen liquid yeast without major process changes.

Yes. SmartBev™ FLY allows breweries to maintain selected yeast strains on-site in frozen storage. This helps reduce reliance on maintaining active laboratory cultures and provides greater flexibility when production schedules or product plans change.

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