A “Psychobiotic” is a bacterium, when ingested in adequate amount, has a positive benefit for mental health.
Ted Dinan, M.D., Ph.D, John F. Cryan, Ph.D
APC Microbiome Ireland, University College Cork
Mental health
Mental health is top of mind
We’re all interested in having a better and happier life. And consumers are looking to the emerging science of probiotics and the gut-brain axis for answers1.
There is no health without mental health
80% of consumers globally want to do more to look after their mental well-being2. But what does that mean?
The World Health Organization (WHO) describes mental health as a “state of well-being in which the individual realizes their own abilities, can cope with the normal stresses of life, can work productively and is able to make a contribution to their community”3.
No wonder people are looking for ways to actively support the mind’s ability to thrive. The days of taboo and stigma are behind us, and you can seize this opportunity with innovative and effective biotic solutions.
More to life with good mental health
Mental health plays a role in how we live today and how we age tomorrow. Explore solutions for cognitive health and mental wellness that support everyday well-being and mental engagement.
What’s on your mind?
Whatever it is, let us know. Together, let's address consumers' interest in cognitive health and mental wellness. It’s a question of better health.
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How the microbiome-gut-brain axis works
As old as a "gut feeling"
We’ve always known the gut and brain are connected, but science only recently began discovering how the rich and dynamic communication of the microbial-gut-brain-axis works. In fact, most of the scientific breakthroughs were as recent as the 2010s and 2020s.
The quick overview
The brain and gut communicate in both directions. The brain affects gut function and the microbiome. And gut microbes produce molecules that influence brain function. This two-way link impacts our immunity, digestion, mood, cognitive capabilities, how we respond to stress, and even how we behave5 6 7.
Via the vagus nerve (part 1)
The vagus nerve is a long wandering nerve that runs from the brain stem to our organs, including the intestines.
The brain sends signals via the nerve to the stomach. When we eat, for example, signals travel down the vagus nerve and prompt the release of digestive juices and enzymes that help break down food8.
Via the vagus nerve (part 2)
Via the blood brain barrier
Via hormone production
Stress affects the gut via the hypothalamic-pituitary-adrenal axis. It triggers a cascade of hormone production, for example cortisol. Cortisol can influence intestinal permeability, while other stress hormones affect the environment within the gut and the composition of the microbes that live there.13
Learn more about mental health
Mental health brochure
Read more about this rapidly growing market and the scientific evidence behind ProbioBrain™ and L. rhamnosus, LGG™ including their proposed modes of action.
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