Class: Probiotic
Format: Multiple formats
L. rhamnosus, LGG™
Lacticaseibacillus rhamnosus, LGG™ (shortened to LGG™) is the world’s most documented probiotic strain, with more than 2,500 scientific publications, including more than 300 clinical study publications. In fact, the World Gastroenterology Organization’s Global Guidelines for Probiotics and Prebiotics1lists LGG™ as having documented, positive results in five gut-related health areas. It’s also listed in ESPGHAN’s position paper on gut microbiota and modification recommendations for children2.
With advanced genomic sequencing, we mapped the complete genome of the LGG™ strain. The results show it has remained stable and is identical to the original strain isolated in 19853, 4. It’s been used globally in food and dietary supplements since 1990, with no safety concerns.
LGG™ is the natural choice for functional food and dietary supplement providers who refuse to compromise on quality and probiotic benefits across multiple health areas.
Product features, details and benefits
- World’s most documented probiotic.
- Well-known to support gut and immune health.
- Shown to support cognitive health
- Available in infant grade.
- Shown to support skin and oral health.
- Clinically studied across life stages.
The LGG™ strain (DSM 33156) was isolated from a healthy human in 1985. First launched in 1990, it’s used worldwide in applications such as baby formula, dietary supplements and fermented milk products like yogurt.
In 2020, over 261 validated species under the genus Lactobacillus were reclassified based on gene sequencing. LGG™ was among them5.
LGG™ is acid and bile stable. It’s produced in a certified GMP Facility, FSSC22000 certified incl. ISO22000.
The LGG™ logo can be used on packaging subject to agreement. LGG™ is a trademark of Chr. Hansen A/S, part of Novonesis Group.
This product contains microbials. While microbial products are safe to use in consumer applications, they must be handled correctly in production environments to ensure that workers do not inhale organic dust and bioaerosols.
Please follow the precautionary handling recommendations below:
• Avoid breathing dust/fume/gas/mist/vapors/spray
• Avoid contact with eyes, skin, or clothing
• In case of inadequate ventilation wear respiratory protection
• IF INHALED: Remove person to fresh air and keep comfortable for breathing
• Store in a dry place. Store in a closed container
• Dispose of contents/containers in accordance with local regulations
More information about safe-handling of microbial products is available on request.
For recommendations on how to safely handle the microbial product, please visit the guide.
Health benefits
The highly researched L. rhamnosus, LGG™ probiotic strain has been studied extensively alone and in combination with other probiotics. This wealth of clinical documentation demonstrates the strain’s benefits and safety across life stages and health areas. Below are results from some of the research:
ADULTS
Gastrointestinal health:
- Shown to promote gastrointestinal comfort6.
- In clinical studies, people reported fewer digestive discomforts – such as nausea, taste disturbance and bloating – when supplementing with LGG6, 7, 8, 9.
- Associated with fewer incidences of gastrointestinal distress and longer periods of gastrointestinal comfort10, 11.
- Helps reduce the risk of occasional loose stools while traveling12.
Immune health:
- Shown to support a healthy immune response13
- LGG™, in combination with the BB-12™ strain, have been shown to support respiratory tract comfort14.
Mental health:
- Shown to support cognitive function in middle-aged and elderly subjects15
INFANTS AND CHILDREN
Gastrointestinal health - associated with:
- Supporting gastrointestinal comfort16
- Reduced episodes of occasional loose stools and nausea16
- Reduced duration of occasional loose stools17, 18, 19
- Beneficial effects on the intestinal barrier system20.
Respiratory tract support: Studies on infants, toddlers and children supplementing with LGG™ have shown that the strain may:
- Support normal respiratory tract health4, 21
- Support respiratory well-being21
- Support more consistent school attendance21
Oral health: Based on human studies and microbiological evaluation, the combination of LGG™ and L. CASEI 431™ has been associated with:
Skin health:
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